Alunacedase alfa Antibody

SKU: orb2276894

Description

Alunacedase alfa (APN-01) is a recombinant human soluble ACE2 (hrsACE2) that acts as a decoy receptor for SARS-CoV-2, inhibiting viral entry. This investigational protein is utilized in research models of COVID-19, pulmonary hypertension, and acute lung injury to study ACE2-mediated pathways in vitro and in vivo.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	2416824-55-8
Purity	99.1% (SDS-PAGE); 99.9% (SEC-HPLC)
Target	RAAS

Bioactivity

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Target IC50	SARS-CoV-2 spike glycoprotein:1.2 nM (Kd)
In Vitro	Alunacedase alfa exhibits high-affinity binding to the SARS-CoV-2 spike glycoprotein, with an estimated affinity of roughly 1.2 nM.

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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APN 01, APN-01, ACE2, GSK 2586881, GSK2586881, HrsACE2

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Gene Symbol

RAAS

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