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(Aminooxy)acetamide-Val-Cit-PAB-MMAE

SKU: orb2279054

Description

This small molecule intermediate is used to synthesize antibody-drug conjugates (ADCs) for cancer research. It enables the attachment of the cytotoxic payload MMAE to antibodies like Trastuzumab via a polyamide linker, forming ADCs for targeted in vitro and in vivo therapeutic studies.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2446645-88-9
MW1196.48
FormulaC60H97N11O14
SMILES[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC(CON)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information