Aminopurvalanol A

SKU: orb1306043

Description

Aminopurvalanol A is a potent, selective, and cell-permeable cyclin-dependent kinase (CDK) inhibitor. It effectively targets CDK1, CDK2, and CDK5 complexes with IC50 values in the 20-33 nM range. This compound is widely used in biochemical and cellular research to study cell cycle regulation, neuronal function, and apoptosis in both in vitro and in vivo models.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	220792-57-4
MW	403.91
Purity	99.73% (May vary between batches)
Formula	C₁₉H₂₆ClN₇O
SMILES	CC(C)[C@H](CO)Nc1nc(Nc2cc(N)cc(Cl)c2)c2ncn(C(C)C)c2n1
Target	CDK,Apoptosis
Solubility	DMSO:55 mg/mL (136.17 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.95 mM);Ethanol:10 mg/mL (24.76 mM)

Bioactivity

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Target IC50	CDK5-p35:20 nM\|CDK2-CyclinE:28 nM\|CDK2-CyclinA:33 nM\|CDK1-CyclinB:33 nM

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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sperm fertilizing ability, inhibit, G2/M-phase transition, Inhibitor, actin polymerization, cancer cell differention, Aminopurvalanol A, Apoptosis, Cyclins, Cyclin dependent kinase, cdk5/P35, CDK2/CyclinA, cdk2/CyclinE, cdk1/CyclinB, CDK

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Compound Identifiers

PubChem CID

6604931 ↗

Key Properties

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No computed properties available.

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