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Amylin, amide, rat acetate(124447-81-0,free base)

SKU: orb1296702

Description

Amylin, amide, rat acetate is a high-affinity, potent agonist selective for AMY1 and AMY3 receptors, with variable activity at AMY2 receptors. This peptide is a key research tool for investigating amylin receptor signaling in metabolic studies, including in vitro binding assays and in vivo models of energy homeostasis and glucose regulation.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW3980.45
Purity98.50% (May vary between batches)
FormulaC169H276N52O55S2
SMILES[H]N[C@H](C(N[C@H]1CSSC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N2CCC[C@H]2C(N[C@H](C(N[C@H](C(N3CCC[C@H]3C(N4CCC[C@H]4C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC5=CC=C(C=C5)O)=O)[C@H](O)C)=O)CC(N)=O)=O)CO)=O)=O)C(C)C)=O)CC(N)=O)=O)[C@H](O)C)=O)=O)=O)CC(C)C)=O)C(C)C)=O)=O)=O)CC(C)C)=O)CC(N)=O)=O)CC(N)=O)=O)CO)=O)CO)=O)CCCNC(N)=N)=O)C(C)C)=O)CC(C)C)=O)CC6=CC=CC=C6)=O)CC(N)=O)=O)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)[C@H](O)C)=O)C)=O)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H]([C@H](O)C)NC([C@@H](NC1=O)CC(N)=O)=O)=O)C)=O)=O)=O)CCCCN.CC(O)=O
TargetAmylin Receptor

Bioactivity

In Vivo
Amylin is an important 37 amino acid glucoregulatory hormone with great potential to target metabolic diseases. Amylin is a member of the calcitonin (CT) family of peptides, which includes CT itself, the CGRPs comprising two variants (αCGRP and βCGRP), adrenomedullin (AM) and AM2 (intermedin). Amylin is a centrally acting, neuroendocrine hormone synthesized with insulin in the beta cells of pancreatic islets. Amylin regulates glucose homeostasis by inhibiting gastric emptying, inhibiting the release of the counter-regulatory hormone glucagon and inducing meal-ending satiety. Amylin functions as a glucoregulatory and satiety-inducing hormone, which is protective against postprandial spikes in blood glucose and overeating.

Storage & Handling

Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Amylin Receptor, amylin, AmylinReceptor, Amylin, amide, rat acetate(124447 81 0,free base), Amylin, amide, rat acetate(124447810,free base), Amylin, amide, rat acetate(124447-81-0,free base)
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 220.00
5 mg
$ 480.00
10 mg
$ 640.00
25 mg
$ 960.00
50 mg
$ 1,220.00
100 mg
$ 1,700.00
200 mg
$ 2,270.00
DispatchUsually dispatched within 3-5 working days
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