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CD74 Biosimilar Antibody
Description
Images & Validation
−| Tested Applications | ELISA, FC |
|---|---|
| Dilution range | ELISA 1:5000-10000, Flow Cyt 1:100 |
| Reactivity | Human |
Key Properties
−| Antibody Type | Biosimilar Antibody |
|---|---|
| Host | Human Humanized |
| Clonality | Monoclonal |
| Isotype | Human IgG1(K214R) - kappa |
| Target | CD74 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Disclaimer | For research use only |
Alternative Names
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Flow cytometry analysis with 15 μg/mL Anti-CD74 (milatuzumab biosimilar) mAb (orb1826918) on Expi293 cells transfected with Human CD74 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CD74 Protein, hFc Tag (orb1173822) can bind Anti-CD74 (milatuzumab biosimilar) mAb (orb1826918) in a linear range of 0.64–16 ng/ml. In order to specifically detect orb1826918, mouse anti-human Fab-specific antibody was used as detection antibody.

Flow cytometry analysis of antigen binding of anti-human CD74 mAb (orb1826918). (A) orb1826918 does not bind to 293T cells that do not express CD74. (B) A clear peak shift of orb1826918 was seen compared to the control when incubated with CD74-expressing Raji cells, indicating strong binding of orb1826918 to CD74. Antibodies were incubated at 5 μg/mL.
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CD74 Biosimilar Antibody (orb1826918)
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