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CLDN18.2 Antibody
SKU: orb1806239
Description
Images & Validation
−Item 1 of 4
| Tested Applications | ELISA, FA, FACS, In vivo |
|---|---|
| Reactivity | Human |
Key Properties
−| Clonality | Monoclonal |
|---|---|
| Target | CLDN18.2 |
| Source/Expression System | CHO |
| Molecular Weight | 150 kDa |
| Purity | >95% |
| Purification | Protein A |
| Endotoxin | <0.001 EU/ug |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Buffer/Preservatives | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Concentration | Batch dependent |
| Disclaimer | For research use only |
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Anti-CLDN18.2 Reference Antibody (zolbetuximab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-CLDN18.2 Reference Antibody (zolbetuximab)is more than 96.05% ;determined by SEC-HPLC.
Immobilized human CLDN18.2 VLP at 2 μg/mL can bind Anti-CLDN18.2 Reference Antibody (zolbetuximab);EC50=0.07951μg/mL.
Zolbetuximab inhibited the tumor growth of CLDN18.2-MC38 (Mouse colorectal cancer cells) on C57BL/6N mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 42.3% at 10 mpk at D25.
Quick Database Links
Gene Symbol
CLDN18.2
UniProt
UniProt Details
− No UniProt data available
Documents Download
Datasheet
Product Information
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Protocol Information
FACS
Fluorescence-Activated Cell Sorting (FC, Flow cytometry)
ELISA
Enzyme-linked Immunosorbent Assay (EIA)
CLDN18.2 Antibody (orb1806239)
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