Anti-Integrin alpha 4 [Natalizumab]

SKU: orb411591

Description

Human monoclonal antibody to Integrin alpha 4

Images & Validation

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Item 1 of 1

Tested Applications	Blocking, FC
Reactivity	Human

Key Properties

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Host	Human
Clonality	Monoclonal
Isotype	IgG4
Clone No.	Natalizumab
Immunogen	The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
Target	Integrin alpha 4
Purity	Purified
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	PBS with 0.02% Proclin 300.
Concentration	1 mg/ml
Disclaimer	For research use only

Alternative Names

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CD49D; alpha 4 subunit of VLA-4 receptor; ITGA4; Integrin alpha-IV

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Flow-cytometry using the anti-Integrin alpha 4 research biosimilar antibody Natalizumab Human lymphocytes were stained with an isotype control (orb256390, panel A) or the rabbit-chimeric version of Natalizumab (orb411592, panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody and cells analysed on a FACSCanto flow-cytometer.

Quick Database Links

Gene Symbol

Integrin alpha 4

UniProt

P13612

UniProt Details

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No UniProt data available

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Protocol Information

Flow Cytometry

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