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TSLP Antibody
SKU: orb1805495
Description
Images & Validation
−Item 1 of 6
| Tested Applications | ELISA, FA, FACS, In vivo |
|---|---|
| Reactivity | Human, Monkey |
Key Properties
−| Clonality | Monoclonal |
|---|---|
| Target | TSLP |
| Source/Expression System | CHO |
| Molecular Weight | 144.6 kDa |
| Purity | >95% |
| Purification | Protein A |
| Endotoxin | <0.001 EU/ug |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Buffer/Preservatives | 100 mM Proline/Acetic acid 20mM Arginine pH 5.0 |
| Concentration | Batch dependent |
| Disclaimer | For research use only |
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Anti-TSLP Reference Antibody (tezepelumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-TSLP Reference Antibody (tezepelumab)is more than 98.64% ;determined by SEC-HPLC.
Immobilized human TSLP His at 2 μg/mL can bind Anti-TSLP Reference Antibody (tezepelumab);EC50=0.0518μg/mL.
Anti-TSLP Reference Antibody (tezepelumab)-induced FACS Blocking activity was evaluated using TSLPR/IL7R-CHO-K. The IC50 was approximately 0.0802 μg/mL.
Tezepelumab reduced levels of IL13 in BALF of OVA asthma model on B-hTSLP/hTSLPR mice. The result showed significant IL13 inhibition effects at 15 mpk.
Quick Database Links
Gene Symbol
TSLP
UniProt
UniProt Details
− No UniProt data available
Documents Download
Datasheet
Product Information
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Protocol Information
FACS
Fluorescence-Activated Cell Sorting (FC, Flow cytometry)
ELISA
Enzyme-linked Immunosorbent Assay (EIA)
TSLP Antibody (orb1805495)
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