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Antidepressant agent 8

SKU: orb2944865

Description

Compound 1f is a selective GluN1/2A NMDA receptor antagonist (IC50 = 2.94 µM) with demonstrated blood-brain barrier permeability. It exhibits antidepressant-like activity in a zebrafish depression model, supporting its utility in neuroscience research for studying NMDA receptor function and depression pathophysiology.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3066104-04-6
MW394.53
FormulaC18H23FN4OS2
SMILESO=C(NCC1CCCCC1)CSC2=NN=C(S2)NCC=3C=CC=C(F)C3
TargetiGluR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information