Antitumor agent-149

SKU: orb2566972

Description

Antitumor agent-149 (Compound 3) is an Echinomycin analog that blocks HIF-1α transcriptional activity. This mechanism induces apoptosis in cancer cells and has demonstrated efficacy in suppressing tumor growth in both in vitro studies and an SW620 xenograft mouse model.

Research Area

Cell Biology

Images & Validation

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Key Properties

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CAS Number	2368983-54-2
MW	1085.19
Formula	C₅₂H₆₄N₁₀O₁₄S
SMILES	C(N[C@@H]1COC(=O)[C@H](C(C)C)N(C)C(=O)[C@@]2(CSC[C@](N(C)C(=O)[C@H](C)NC1=O)(C(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)C3=NC4=C(C=C3O)C=CC=C4)C(=O)N[C@@H](C)C(=O)N2C)[H])[H])(=O)C5=NC6=C(C=C5O)C=CC=C6
Target	Apoptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

155766339 ↗

Key Properties

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No computed properties available.

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