Antitumor agent-81

SKU: orb1744829

Description

Antitumor agent-81 is a small molecule agonist that enhances the P62-RNF168 interaction, thereby inhibiting RNF168-mediated H2A ubiquitination and homologous recombination DNA repair. It demonstrates potent, dose-dependent suppression of tumor growth in mouse xenograft models, making it a valuable research tool for studying DNA damage response and cancer therapeutics.

Research Area

Cell Biology, Protein Biochemistry

Images & Validation

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Key Properties

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CAS Number	2765180-17-2
MW	393.4
Formula	C₁₉H₁₉N₇O₃
SMILES	O(C)C=1C=C(N2C=C(N=N2)C3=CC4=C(C=C3)N=C(N)N=C4N)C=C(OC)C1OC
Target	Others,E1/E2/E3 Enzyme,p62,Apoptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

163214076 ↗

Key Properties

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No computed properties available.

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