(-)-Apomorphine hydrochloride hydrate

SKU: orb2283774

Description

(-)-Apomorphine hydrochloride hydrate is a broad-spectrum dopamine agonist and ferroptosis inhibitor with high affinity for D1-like receptors. It serves as a research tool for studying mitochondrial disorders, Parkinson's disease models, and cell death mechanisms in both in vitro and in vivo experimental systems.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	58117-94-5
MW	303.8
Formula	C₁₇H₁₇NO₂?HCl[XH₂O]
SMILES	CN1[C@]2(C=3C(C=4C(C2)=CC=C(O)C4O)=CC=CC3CC1)[H].Cl.O xH2O
Target	Dopamine Receptor,Ferroptosis

Bioactivity

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In Vitro

(-)-Apomorphine hydrochloride hydrate prevented ferroptosis in fibroblasts from various types of mitochondrial diseases as well as in normal controls. (-)-Apomorphine hydrochloride hydrate induced significant downregulation of PTSG2 and suppressed lipid peroxide to the same extent as other inhibitors of ferroptosis also indicate that (-)-Apomorphine hydrochloride hydrate suppresses ferroptosis.

Storage & Handling

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Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Ferroptosis, DopamineReceptor, Dopamine Receptor

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Compound Identifiers

PubChem CID

6852399 ↗

Key Properties

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No computed properties available.

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