Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

AR-A014418

SKU: orb1224963

Description

A potent, specific ATP-competitive inhibitor of GSK-3β with Ki/IC50 of 38/104 nM; shows no significantly inhibition on CDK2, CDK5 (IC50>100 uM) or 26 other kinases; inhibits tau phosphorylation at a GSK3-specific site (Ser-396) in cells and protects N2A neuroblastoma cells against cell death mediated by inhibition of PI3K/Akt pathway.

Images & Validation

Key Properties

CAS Number487021-52-3
MW308.3131
Purity>98% (HPLC)
FormulaC12H12N4O4S
SMILESCOc1ccc(cc1)CNC(=O)Nc2ncc(s2)[N+](=O)[O-]
TargetGSK-3
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AR-AO 14418 | AR 0133418 | AR 014418 | GSK 3β inhibitor

Similar Products

  • AR-A 014418 [orb1307275]

    >98%

    487021-52-3

    308.32

    C12H12N4O4S

    5 mg, 25 mg
  • Enzastaurin [orb1225957]

    >98% (HPLC)

    170364-57-5

    515.605

    C32H29N5O2

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

500 mg
5 mg
$ 90.00
10 mg
$ 100.00
25 mg
$ 160.00
50 mg
$ 270.00
100 mg
$ 460.00
200 mg
$ 590.00