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ARN5187 trihydrochloride

SKU: orb1686566

Description

ARN5187 trihydrochloride is a lysosomotropic ligand targeting REV-ERBβ, disrupting its transcriptional activity and inhibiting autophagy. This compound exhibits cytotoxic effects and induces apoptosis, making it a useful research tool for studying circadian biology, lysosomal function, and cell death mechanisms in both cellular and animal models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1700693-96-4
MW506.912
FormulaC24H35Cl3FN3O
SMILESCl.Cl.Cl.CN1CCN(Cc2cc(CNC3(CCCC3)c3ccccc3F)ccc2O)CC1
TargetAutophagy,Others,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

ARN5187 trihydrochloride (orb1686566)

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