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AS 1269574

SKU: orb1218157

Description

AS 1269574 is a potent, orally available GPR119 agonist. AS1269574 has the potential for the research of type 2 diabetes.

Images & Validation

Key Properties

CAS Number330981-72-1
MW308.18
Purity>98% (HPLC)
FormulaC13H14BrN3O
SMILESCC1=CC(=NC(=N1)C2=CC=C(C=C2)Br)NCCO
TargetGPR
SolubilityDMSO:250 mg/mL (811.24 mM; Need ultrasonic)

Bioactivity

In Vivo
AS1269574 sgnificantly reduced the blood glucose AUC after 2 h (AUC0-2h) of administration. Animal model: Eight-week-old ICR mice. Dosage: 100 mg/kg. Administration: p.o. Result: Sgnificantly reduced the blood glucose AUC after 2 h (AUC0-2h) of administration. Similarly, plasma insulin AUC0-2h was significantly higher in the mice.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AS1269574

Similar Products

  • AS1269574 [orb1306270]

    99.98% (May vary between batches)

    330981-72-1

    308.17

    C13H14BrN3O

    1 ml x 10 mM (in DMSO), 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
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Protocol Information

Available Sizes

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2 mg
$ 80.00
5 mg
$ 120.00
10 mg
$ 190.00
25 mg
$ 340.00
50 mg
$ 520.00
100 mg
$ 770.00
500 mg
$ 1,680.00