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Aspirin (Standard)

SKU: orb3025904

Description

Aspirin (Standard) is the standard substance of Aspirin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Aspirin is an orally active, selective, and irreversible inhibitor of COX-1 and COX-2 with IC₅₀ values of 5 and 210 μg/mL, respectively. It induces apoptosis, inhibits NF-κB activation and platelet prostaglandin synthesis, thereby preventing thrombosis. Additionally, it acts as a histone deacetylase inhibitor that upregulates p21, exhibiting anti-inflammatory, antipyretic, analgesic, and anti-platelet aggregation activities. Aspirin is commonly used to induce gastric ulcer models.

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Key Properties

CAS Number50-78-2
MW180.16
FormulaC9H8O4
SMILESCC(=O)OC1=CC=CC=C1C(O)=O
TargetAutophagy,Virus Protease,Mitophagy,p38 MAPK,COX,NF-κB,Apoptosis,Caspase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Aspirin (Standard) (orb3025904)

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