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ATH686

SKU: orb1299605

Description

ATH686 is a potent and selective FLT3 kinase inhibitor. It is a valuable research tool for studying acute myeloid leukemia (AML), demonstrating activity in both cellular assays and in vivo models of FLT3-driven disease.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number853299-52-2
MW515.53
Purity99.90% (May vary between batches)
FormulaC25H28F3N7O2
SMILESCCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccnc(N)n4)cc3)cc2C(F)(F)F)CC1
TargetFLT,Apoptosis
SolubilityDMSO:100 mg/mL (193.98 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.76 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Fms like tyrosine kinase 3, FLT3, Inhibitor, inhibit, ATH686, ATH-686, ATH 686, Apoptosis, autophosphorylation, ATP-competitive, antileukemic, Cluster of differentiation antigen 135, CD135
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Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

ATH686 (orb1299605)

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% DMSO +
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% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 1,950.00
5 mg
¥ 4,160.00
1 ml x 10 mM (in DMSO)
¥ 4,420.00
10 mg
¥ 6,240.00
25 mg
¥ 10,270.00
50 mg
¥ 13,390.00
100 mg
¥ 18,200.00
DispatchUsually dispatched within 3-5 working days
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