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ATX-IN-1

SKU: orb2944381

Description

ATX-IN-1 (compound 35) is a potent, orally bioavailable ATX inhibitor (IC50 = 0.7 nM) with anti-inflammatory and anti-fibrotic properties. It suppresses the TGF-β/Smad pathway and collagen deposition, demonstrating efficacy in a bleomycin-induced pulmonary fibrosis mouse model, making it a valuable tool for fibrosis and inflammation research.

Research Area

Metabolism Research

Images & Validation

Key Properties

MW486.48
FormulaC25H22N6O5
TargetPDE

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information