Aurintricarboxylic acid

SKU: orb1299026

Description

Aurintricarboxylic acid is a potent small-molecule inhibitor of nucleases, including ribonuclease and topoisomerase II, acting by blocking nucleic acid-enzyme binding. It is widely used in biochemical research to study nucleic acid metabolism and protein interactions in both in vitro and cell-based assays.

Research Area

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	4431-00-9
MW	422.34
Purity	97.10% (May vary between batches)
Formula	C₂₂H₁₄O₉
SMILES	OC(=O)C1=CC(C=CC1=O)=C(c1ccc(O)c(c1)C(O)=O)c1ccc(O)c(c1)C(O)=O
Target	Influenza Virus,Topoisomerase,MicroRNA,P2X Receptor,Apoptosis
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.47 mM);DMSO:125 mg/mL (295.97 mM)

Bioactivity

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Target IC50	P2X3 (rat):72.9 nM\|MicroRNA:0.47 μM\|P2X1 (rat):8.6 nM
In Vitro	Aurintricarboxylic acid (ATA) is a known Stp1 inhibitor with an IC50 of 1.03 μM.

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Topoisomerase II, Topoisomerase, rP2X1, rP2X3, receptor, sensory, P2X, P2X Receptor, P2XReceptor, P2XRs, TWEAK, TWEAK-Fn14, anti-influenza, Apoptosis, Aurintricarboxylic acid, ATP-gated, ATA, cough, chronic, neurotransmission, neuropathic, MicroRNA, miRNA, NSC 4056, NSC4056, NSC-4056, pain, inhibit, InfluenzaVirus, Influenza Virus, Inhibitor, family, Fn14, glioblastoma

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Compound Identifiers

PubChem CID

2259 ↗

Key Properties

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No computed properties available.

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