Autophagy agonist-1

SKU: orb2944430

Description

Autophagyagonist-1 is a small molecule autophagy inducer with selective anticancer activity, showing potent cytotoxicity in HepG2 cells (IC50 8.8 µM) while sparing normal cells. It promotes autophagy and mitophagy via LC3 and PINK1 accumulation and induces G1/S cell cycle arrest by modulating CDK4, Cyclin D1, and p21, making it a useful research tool for studying autophagy-related pathways in cancer models.

Research Area

Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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MW	559.7
Formula	C₃₃H₄₁N₃O₅
Target	CDK,PTEN,ATG,Autophagy

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

CDK,PTEN,ATG,Autophagy

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