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Autophagy agonist-1

SKU: orb2944430

Description

Autophagyagonist-1 is a small molecule autophagy inducer with selective anticancer activity, showing potent cytotoxicity in HepG2 cells (IC50 8.8 µM) while sparing normal cells. It promotes autophagy and mitophagy via LC3 and PINK1 accumulation and induces G1/S cell cycle arrest by modulating CDK4, Cyclin D1, and p21, making it a useful research tool for studying autophagy-related pathways in cancer models.

Research Area

Cell Biology, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Images & Validation

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Autophagy agonist-1

Key Properties

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MW559.7
FormulaC33H41N3O5
TargetAutophagy,PTEN,ATG,CDK

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

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Gene Symbol
Autophagy,PTEN,ATG,CDK

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