Avenanthramide C

SKU: orb2802060

Description

Avenanthramide C is an orally available natural alkaloid with antioxidant/inflammatory properties that reduces the expression of TNF-a, BAK, IL-1b, and Bcl-2; reverses memory and behavioral deficits in Alzheimer's disease, with a reduction in caspase-3 cleavage and an increase in levels of pS9GSK-3β and IL-10, is able to bind α1A adrenergic and stimulate AMPK; can attenuate noise and drug-induced hearing loss.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	116764-15-9
MW	315.28
Purity	99.40%
Formula	C₁₆H₁₃NO₆
SMILES	N(C(/C=C/C1=CC(O)=C(O)C=C1)=O)C2=C(C(O)=O)C=C(O)C=C2
Target	Caspase,TNF,Bcl-2 Family,AMPK,Adrenergic Receptor,IL Receptor

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Caspase,TNF,Bcl-2 Family,AMPK,Adrenergic Receptor,IL Receptor

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