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Batefenterol

SKU: orb1224092

Description

A bifunctional M3 mAChR antagonist and β2-adrenoceptor agonist (MABA) with pKi/pEC50 of 8.7/9.6 for hM3/hβ2 respectively; shows weak effect on β1; the first MABA compound to enter clinical trials and demonstrate proof of concept and efficacy in COPD.COPD Phase 2 Clinical.

Images & Validation

Key Properties

CAS Number743461-65-6
MW740.2438
Purity>98% (HPLC)
FormulaC40H42ClN5O7
SMILESO=C(OC1CCNCC1)NC2=CC=CC=C2(CCC(NC3=CC(OC)=C(CNC[C@H](O)C4=CC=C(O)C5=C4C=CC(N5)=O)C=C3Cl)=O)C6=CC=CC=C6
TargetmAChR
SolubilityDMSO: 10 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GSK961081 | TD-5959

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Quality Guarantee

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Protocol Information

Available Sizes

Select a size below

200 mg
500 mg
2 mg
$ 170.00
5 mg
$ 250.00
10 mg
$ 370.00
25 mg
$ 670.00
50 mg
$ 990.00
100 mg
$ 1,380.00