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BAY 1892005

SKU: orb1962244

Description

BAY 1892005 is a small molecule p53 modulator that targets the p53 condenser, offering a tool to investigate diseases linked to misfolded p53 protein. It is utilized in both in vitro and in vivo research to study p53-dependent pathways in oncology and genetic disorders.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number2036352-13-1
MW270.71
Purity99.62% (May vary between batches)
FormulaC11H8ClFN2OS
SMILESO=C(NC1=NC(=CS1)C=2C=CC=CC2F)CCl
TargetMDM-2/p53,p53
SolubilityDMSO:65 mg/mL (240.11 mM)

Bioactivity

Target IC50
p53-mutant:11.2 μM|H358 cells:11.1 μM
In Vitro
In p53-mutant cell lines Huh7 (IC50=11.2 μM) and H358 (IC50=11.1 μM), BAY 1892005 inhibits cell proliferation.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

p53, BAY1892005
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 100.00
5 mg
$ 180.00
10 mg
$ 270.00
25 mg
$ 410.00
50 mg
$ 570.00
100 mg
$ 750.00
DispatchUsually dispatched within 5-10 working days
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