BC 11 hydrobromide

SKU: orb1704663

Description

BC-11 hydrobromide is a selective dual inhibitor of TMPRSS2 and urokinase (uPA). Its mechanism involves reducing mitochondrial function, increasing ROS generation, and inducing apoptosis, making it a useful research tool for studying breast cancer in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Protein Biochemistry

Images & Validation

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Key Properties

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CAS Number	443776-49-6
MW	290.97
Purity	98.07%
Formula	C₈H₁₂BBrN₂O₂S
SMILES	Br.N=C(SCC1=CC=C(C=C1)B(O)O)N
Target	Apoptosis,SARS-CoV,Serine Protease,ROS,PAI-1
Solubility	H2O:15 mg/mL (51.55 mM);DMSO:100 mg/mL (343.68 mM)

Bioactivity

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Target IC50	uPA:8.2 μM

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Apoptosis, BC11 Hydrobromide, BC-11 Hydrobromide, uPA, ROS, SerineProtease, Serine Protease

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Compound Identifiers

PubChem CID

78243712 ↗

Key Properties

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No computed properties available.

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