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BET-IN-23

SKU: orb2566833

Description

BET-IN-23 is a potent and selective BD2-targeting BET inhibitor (IC50 = 2.9 nM). It demonstrates anti-leukemic activity in vitro by suppressing AML cell proliferation, inducing cell cycle arrest and apoptosis. Its research applications include epigenetic and cancer biology studies, with potential for in vivo efficacy investigation.

Research Area

Cell Biology, Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number2953287-57-3
MW523.60
FormulaC29H34FN3O5
SMILESO(C1=C(C=C(C(C)(C)O)C=C1)C=2C(NCC(=O)N3CCOCC3)=CC(=O)N(C)C2)C4=C(C)C=C(F)C=C4C
TargetEpigenetic Reader Domain,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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BET-IN-23 (orb2566833)

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