Cart summary

You have no items in your shopping cart.

BIO

SKU: orb1224292

Description

A cell-permeable derivative of 6-bromoindirubin that displays selective inhibition of GSK-3 with IC50 of 5 nM; also inhibit CDK1/Cyclin B and CDK5/p25 (IC50, 320 nM and 83 nM); maintains the undifferentiated phenotype in HESCs and MESCs, sustains the expression of Oct-3/4, Rex-1 and Nanog; promotes proliferation in mammalian cardiomyocytes.

Images & Validation

Key Properties

CAS Number667463-62-9
MW356.1735
Purity>98% (HPLC)
FormulaC16H10BrN3O2
SMILESO=C(/C1=C2NC3=C(C\2=N/O)C=CC=C3)NC4=C1C=CC(Br)=C4
TargetGSK-3
SolubilityDMSO: ≥ 23 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

6BIO | 6-BIO | GSK 3 IX | GSK 3 Inhibitor IX | MLS 2052 | MLS2052

Similar Products

  • Matriptase Reference Antibody [orb1806006]

    ELISA,  FA,  FACS,  In vivo

    Human

    Monoclonal

    Unconjugated

    100 μg, 1 mg
  • CXADR Reference Antibody [orb1806233]

    ELISA,  FA,  FACS,  In vivo

    Human

    Monoclonal

    Unconjugated

    1 mg, 100 μg
  • CRTAM / CD355 Reference Antibody [orb1806235]

    ELISA,  FA,  FACS,  In vivo

    Human

    Monoclonal

    Unconjugated

    1 mg, 100 μg
  • CXADR Reference Antibody [orb1817618]

    FC,  Kinetics

    Human

    Monoclonal

    Unconjugated

    100 μg
  • Matriptase Reference Antibody [orb1817512]

    FC,  Kinetics

    Human, Mouse

    Monoclonal

    Unconjugated

    100 μg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

BIO (orb1224292)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
¥ 1,300.00
5 mg
¥ 1,690.00
10 mg
¥ 2,080.00
25 mg
¥ 4,420.00
50 mg
¥ 7,540.00
100 mg
¥ 11,050.00
500 mg
¥ 23,140.00