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bis(7)-Tacrine

SKU: orb1704896

Description

Bis(7)-tacrine dihydrochloride is a dimeric derivative of tacrine that acts as a potent acetylcholinesterase (AChE) inhibitor, NMDA receptor blocker, and GABA A receptor antagonist. It has demonstrated neuroprotective effects against glutamate-induced apoptosis in vitro and shows potential for Alzheimer's disease research in both cellular and animal models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number224445-12-9
MW565.63
FormulaC33H42Cl2N4
SMILESCl.Cl.C(CCCNc1c2CCCCc2nc2ccccc12)CCCNc1c2CCCCc2nc2ccccc12
TargetOthers,GABA Receptor,iGluR,Cholinesterase (ChE)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

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5 mg
$ 330.00
10 mg
$ 590.00
100 mg
$ 3,960.00
DispatchUsually dispatched within 6-8 weeks
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