Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

BMS-564929

SKU: orb1707535

Description

BMS-564929 is a potent androgen receptor agonist that promotes lipogenic enzyme activity while reducing visceral adipose tissue and lipid content. It downregulates key lipogenic genes including acetyl-CoA carboxylase, FASN, and SCD, making it a valuable research tool for studying metabolic disorders in both in vitro and in vivo models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number627530-84-1
MW305.72
Purity98.17% (May vary between batches)
FormulaC14H12ClN3O3
SMILESO=C1N(C(=O)N2[C@]1([C@H](O)CC2)[H])C3=C(C)C(Cl)=C(C#N)C=C3
TargetAndrogen Receptor
SolubilityDMSO:40 mg/mL (130.84 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.54 mM)

Bioactivity

Target IC50
AR:2.11 nM (Ki)
In Vivo
BMS-564929 (0.00001 - 10 mg/kg,14 days, gavage) is more effective than testosterone in stimulating the growth of the levator anal muscle and has a strong oral activity.
In Vitro
BMS-564929 is a novel, highly effective and orally active non-steroidal tissue-selective androgen receptor (AR) modulator with Ki = 2.11 nM. The EC50 value of BMS-564929 in mouse myoblasts (C2C12) and rat PEC cell lines was 0.44 nM and 8.66 nM, respectively.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BMS564929, BMS-564929, BMS 564929, AndrogenReceptor
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 190.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry