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Brexpiprazole

SKU: orb1223665

Description

Brexpiprazole is a novel D2 dopamine partial agonist.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number913611-97-9
MW433.57
Purity>98% (HPLC)
FormulaC25H27N3O2S
SMILESO=C1NC2=C(C=C1)C=CC(OCCCCN1CCN(CC1)C1=C3C=CSC3=CC=C1)=C2
Target5-HT Receptor
SolubilityDMSO: 10 mM

Bioactivity

In Vivo
Animal model: Male C57BL/6NCrSlc mice, Dizocilpine (0.1 mg/kg) (HY-15084B) induced social recognition deficits. Dosage: 0.01, 0.03 and 0.1 mg/kg. Administration: Oral administration, once. Result: Significantly ameliorated Dizocilpine-induced social recognition deficits, without sedation or a reduction of exploratory behavior.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

OPC 34712

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Protocol Information

Available Sizes

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5 mg
$ 80.00
10 mg
$ 110.00
25 mg
$ 120.00
50 mg
$ 140.00
100 mg
$ 160.00
200 mg
$ 230.00
500 mg
$ 420.00