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BU72

SKU: orb3027993

Description

BU72 is a potent, long-lasting agonist for μ and κ opioid receptors, with partial agonistic activity at the δ opioid receptor (EC50 values of 0.054, 0.033, and 0.58 nM, respectively). It provides strong, enduring analgesic effects primarily mediated through μ opioid receptors. BU72 also exhibits a prolonged duration of activity and can partially reverse morphine-induced analgesia. It is applicable in studies of opioid dependence.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number173265-76-4
MW428.57
FormulaC28H32N2O2
SMILESO(C)[C@@]12[C@@]3([C@@]45C(CC1(C)[C@H](N3)C6=CC=CC=C6)([C@@](CC=7C4=CC(O)=CC7)(N(C)CC5)[H])C=C2)[H]
TargetOpioid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information