Carbetapentane citrate

SKU: orb1310587

Description

Carbetapentane citrate, also known as Pentoxyverine citrate, is a synthetic small molecule antitussive agent used in research. Its mechanism as a non-narcotic cough suppressant makes it relevant for pharmacological studies targeting cough reflexes, including in vitro receptor binding assays and in vivo respiratory models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	23142-01-0
MW	525.59
Purity	99.46%
Formula	C₂₀H₃₁NO₃·C₆H₈O₇
SMILES	OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)CCOCCOC(=O)C1(CCCC1)c1ccccc1
Target	Sigma receptor,AChR
Solubility	10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (4.76 mM);DMSO:65 mg/mL (123.67 mM)

Bioactivity

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In Vivo

Pentoxyverine is an agonist of the σ receptor (σ1 subtype) and an antagonist of the muscarinic acetylcholine receptor (M1 subtype). It possesses anticholinergic properties, theoretically facilitating alveolar relaxation and reducing mucus production. Pentoxyverine (Carbetapentane) Citrate exhibits local anesthetic effects and atropine-like qualities, providing significant suppression of acute cough associated with common upper respiratory tract infections. Furthermore, Pentoxyverine inhibits the cough reflex within the central nervous system, though its precise mechanism of action remains unclear.

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Inhibitor, inhibit, Carbetapentane, Carbetapentane Citrate, Carbetapentane citrate, AChR, Pentoxyverine, Pentoxyverine citrate, Pentoxyverine Citrate

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Compound Identifiers

PubChem CID

90010 ↗

Key Properties

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No computed properties available.

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