Carboxyatractyloside

SKU: orb1299157

Description

Carboxyatractyloside is a natural compound that potently and specifically inhibits the mitochondrial ADP/ATP carrier (AAC), blocking nucleotide exchange. This inhibitor is widely used in biochemical research to study mitochondrial bioenergetics, apoptosis, and the role of the AAC in both cellular and isolated organelle experiments.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	77228-71-8
MW	770.82
Purity	99.56% (May vary between batches)
Formula	C₃₁H₄₆O₁₈S₂
SMILES	C[C@]12[C@]3([C@]4(C[C@@](CC3)(C(=C)[C@@H]4O)[H])CC[C@@]1(C(C(O)=O)(C(O)=O)C[C@@H](O[C@H]5[C@H](OC(CC(C)C)=O)[C@@H](OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@@H](CO)O5)C2)[H])[H]
Target	Others,ROS,Calcium Channel,Mitochondrial Metabolism
Solubility	DMSO:11 mg/mL (14.27 mM);H2O:262.5 mg/mL (340.55 mM)

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Carboxyatractyloside, Carboxyatractyloside tripotassium, Carboxyatractyloside tripotassium salt, Carboxyatractyloside tripotassium salt, C 4992, Gummiferin

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Compound Identifiers

PubChem CID

20055804 ↗

Key Properties

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No computed properties available.

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