CASP12 (N) Antibody, Rabbit Polyclonal

SKU: orb67170

Description

Rabbit polyclonal to CASP12.Inactive caspase-12 (CASP12) belongs to the peptidase C14A family and has no protease activity. Itmay reduce cytokine release in response to bacterial lipopolysaccharide during infections. It alsoreduces activation of NF-kappa-B in response to TNF. The variant Arg-125 (Csp12-L) of CASP12 mayincrease the susceptibility to sever sepsis, and may also increase the mortality rate in sepsis patients.

Research Area

Epigenetics

Images & Validation

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Item 1 of 1

Tested Applications	WB
Dilution range	WB:1:500-1:1000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human CASP12
Molecular Weight	39
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-CASP12 antibody,anti-Inactive caspase12 antibody,anti-CASP12 antibody

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Western blot analysis of total cell extracts from human Hela using CASP12 antibody

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UniProt

Q6UXS9

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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