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CavBeta2 Antibody (APC)

SKU: orb148670

Description

Mouse monoclonal to CaVbeta2 (APC). Cav Beat subunits are involved in the transport of the pore forming alpha1 subunit to the plasma membrane. They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the pore-forming subunit to the target membrane. They also determine the biophysical properties of the calcium channel..

Research Area

Signal Transduction

Images & Validation

Tested ApplicationsAM, ICC, IF, IHC, IP, WB
Dilution RangeWB (1:1000), IHC (1:1000), ICC/IF (1:100)
ReactivityHuman, Mouse, Rat
Application Notes
1 µg/ml was sufficient for detection of Cavβ2 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody

Key Properties

HostMouse
ClonalityMonoclonal
IsotypeIgG1
Clone No.N8b/1 (Formerly sold as S8B-1)
ImmunogenSynthetic peptide amino acids 189-205 of rat CavBeta2
TargetCavBeta2
Molecular Weight78 kDa
PurificationProtein G Purified
ConjugationAPC

Storage & Handling

StorageConjugated antibodies should be stored according to the product label
Buffer/Preservatives95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Concentration1 mg/ml
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Voltage-dependent L-type calcium channel subunit beta-2, Calcium channel voltage-dependent subunit beta 2, CACNB2, CAB2, Cacnlb2, cacnb2
Quality Guarantee

Quality Guarantee

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UniProt Details

No UniProt data available

NCBI Gene Details

No NCBI Gene data available

NCBI Reference Sequences

Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product
ProteinNP_446303

Protocol Information

WB
Western Blot (IB, immunoblot)
View Protocol
IHC
Immunohistochemistry
View Protocol
IF
Immunofluorescence
View Protocol
ICC
Immunocytochemistry
View Protocol
IP
Immunoprecipitation
View Protocol

Available Sizes

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100 μg
$ 660.00
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Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 2-3 weeks
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