CB2R/FAAH modulator-1

SKU: orb1741366

Description

CB2R/FAAH modulator-1 is a dual-action small molecule that acts as a CB2 receptor agonist (Ki=14.8 nM) and a FAAH inhibitor (IC50=4 µM). It modulates inflammatory cytokine production and is utilized in both in vitro and in vivo studies of inflammation, neuroinflammation, and pain research.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

−

Key Properties

−

CAS Number	928892-60-8
MW	361.48
Purity	99.77%
Formula	C₂₄H₂₇NO₂
SMILES	N(C(=O)C1=C(OCC2=CC=CC=C2)C=CC=C1)C34CC5CC(C3)CC(C4)C5
Target	Cannabinoid Receptor,FAAH
Solubility	DMSO:11 mg/mL (30.43 mM)

Bioactivity

−

Target IC50	CB2 receptor:123.6 nM (EC50)\|CB2 receptor:14.8 nM (Kis)\|CB1 receptor:489 nM (EC50)\|CB1 receptor:241.3 nM (Kis)\|FAAH:4 μM
In Vitro	CB2R/FAAH modulator-1 (compound 13; 10 μM; 24 h) reduces TNFα, IFN-γ, IL-1β, and IL-6 production in unstimulated monocytes and macrophages.

Storage & Handling

−

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

−

Cannabinoid Receptor, CannabinoidReceptor, CB2R, CB2R/FAAH modulator1, CB2R/FAAH modulator-1, FAAH

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

17649671 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols