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Cbz-QFR-kbt

SKU: orb3174215

Description

Cbz-QFR-kbt is a ketobenzothiazolone-based TMPRSS2 inhibitor with an IC50 of 0.42 nM. It also exhibits inhibitory activity against Matriptase, Hepsin, HGFA, and Factor Xa, with IC50 values of 1, 1.3, 85, and 85 nM, respectively. Furthermore, Cbz-QFR-kbt demonstrates significant inhibitory effects on SARS-CoV-2 and H1N1 (IC50= 60 nM) and is applicable for antiviral research.

Images & Validation

Key Properties

CAS Number3086979-57-6
MW700.82
FormulaC35H40N8O6S
SMILESC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC(OCC2=CC=CC=C2)=O)CCC(N)=O)=O)=O)CCCNC(=N)N)(=O)C3=NC=4C(S3)=CC=CC4
TargetFactor Xa,Influenza Virus,Serine Protease,SARS-CoV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information