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CCF0058981

SKU: orb1301167

Description

CCF0058981

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number2708934-53-4
MW442.9
FormulaC24H19ClN6O
SMILESC(C(N(CC1=CC(Cl)=CC=C1)C2=CC=C(C=C2)C3=CN=CN3)=O)N4C=5C(N=N4)=CC=CC5
TargetSARS-CoV
SolubilityDMSO:1 mg/mL (2.26 mM)

Bioactivity

In Vitro
CCF0058981 (CCF981) demonstrates inhibition of cytopathic effect (CPE) and plaque reduction in vitro viral replication, with EC50 values of 497 nM and 558 nM, respectively . Additionally, its 50% cytotoxic concentration (CC50) in the CPE antiviral assay exceeds 50 μM . The compound has a half-life (T1/2) of 21.1 minutes and a clearance rate (CLint) of 141 mL/min/kg in human liver microsomes .

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CCF 0058981, CCF0058981, CCF-0058981, SARSCoV, SARS-CoV-2
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

500 mg
1 mg
$ 80.00
2 mg
$ 100.00
5 mg
$ 140.00
1 ml x 10 mM (in DMSO)
$ 140.00
10 mg
$ 210.00
25 mg
$ 390.00
50 mg
$ 520.00
100 mg
$ 640.00