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MPIF-1 Antibody / CCL23 / Myeloid Progenitor Inhibitory Factor 1

SKU: orb1825181

Description

Small inducible cytokine A23 precursor (CCL23), also called CK-b-8 and Myeloid Progenitor Inhibitory Factor 1 (MPIF-1), is a chemokine that binds to the receptor CCR1. It is involved in the immune response and inhibits production of polymorphonuclear leukocytes (PMNs) and monocytes in bone marrow.

Images & Validation

Tested ApplicationsIHC-P
Dilution rangeImmunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
ReactivityHuman
Application Notes
Optimal dilution of the MPIF-1 antibody should be determined by the researcher.

Key Properties

Antibody TypePrimary Antibody
HostMouse
ClonalityMonoclonal
IsotypeMouse IgG2c, kappa
Clone No.CCL23/4036
ImmunogenA recombinant partial protein sequence (within amino acids 1-120) from the human protein was used as the immunogen for the MPIF-1 antibody.
PurificationProtein A/G affinity
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
DisclaimerFor research use only

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MPIF-1 Antibody / CCL23 / Myeloid Progenitor Inhibitory Factor 1

Analysis of a HuProt (TM) microarray containing more than 19000 full-length human proteins using MPIF-1 antibody (clone CCL23/4036). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a mAb to its intended target. A mAb is considered to specific to its intended target, if the mAb has an S-score of at least 2.5. For example, if a mAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that mAb to protein X is equal to 29.

MPIF-1 Antibody / CCL23 / Myeloid Progenitor Inhibitory Factor 1

IHC staining of FFPE human adrenal gland tissue with MPIF-1 antibody (clone CCL23/4036). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

UniProt Details

No UniProt data available

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Protocol Information

IHC-P
Immunohistochemistry Paraffin
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MPIF-1 Antibody / CCL23 / Myeloid Progenitor Inhibitory Factor 1 (orb1825181)

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100 μg
¥ 9,750.00
DispatchUsually dispatched within 5-10 working days
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