CD14 (N) Antibody, Rabbit Polyclonal

SKU: orb67207

Description

Rabbit polyclonal to CD14.Monocyte differentiation antigen CD14 is a cell membrane protein and a component of thelipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4.CD14 cooperates with MD-2 and TLR4 to mediate the innate immune response to bacteriallipopolysaccharide (LPS). CD14 acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-Bactivation, cytokine secretion and the inflammatory response. CD14 up-regulates cell surfacemolecules, including adhesion molecules.

Research Area

Epigenetics, Immunology, Stem Cells

Images & Validation

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Item 1 of 1

Tested Applications	WB
Dilution range	WB:1:1000-1:3000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human CD14
Molecular Weight	40
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-CD14 antibody,anti-Monocyte differentiation antigen CD14 antibody,anti-Myeloid cellspecific leucinerich glycoprotein antibody

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Western blot analysis of total cell extracts from human Jurkat(Lane1) and human T47D(Lane2) using CD14 antibody

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UniProt

P08571

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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