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CDD0102 HCl

SKU: orb1944093

Description

CDD0102 HCl is a potent and selective M1 muscarinic acetylcholine receptor agonist designed for Alzheimer's disease research. It is utilized in both in vitro binding assays and in vivo cognitive studies to investigate cholinergic signaling and potential therapeutic strategies for cognitive disorders.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number1196130-86-5
MW216.67
Purity99.70%
FormulaC8H13ClN4O
SMILESCl.N=1OC(=NC1CC)C2CN=CNC2
TargetAChR

Bioactivity

In Vivo
Following i.p. injections, CDD0102 (CDD-0102) crosses the blood-brain barrier (BBB) in a dose-dependent manner. The LD50 of CDD0102 is 190 mg/kg in toxicological studies after i.p. injections and greater than 1,000 mg/kg following oral administration. In follow-up studies, CDD0102 fully reverses memory deficits associated with IgG-192 saporin administration after oral administration at a dose of 10 mg/kg. No side effects are observed at this dose.
In Vitro
In cell lines expressing M1 receptors, CDD0102 (CDD-0102) is an efficacious muscarinic agonist. CDD0102 exhibits much lower activity at M3 and M5 receptors.

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CDD0102A HCl, M1 mAChR
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Key Properties

No computed properties available.

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Protocol Information

CDD0102 HCl (orb1944093)

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1 mg
¥ 9,620.00
5 mg
¥ 23,920.00
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