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CDH1 (C2) Antibody, Rabbit Polyclonal

SKU: orb66765

Description

Rabbit polyclonal to CDH1.Cadherin-1 (CDH1) is a single-pass membrane protein. Cadherins are calcium-dependent celladhesion proteins. They preferentially interact with themselves in a homophilic manner in connectingcells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved inmechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. It has a potentinvasive suppressor role. It is a ligand for integrin alpha-E/beta-7. Defects in CDH1 are the cause ofhereditary diffuse gastric cancer (HDGC) and are a cause of susceptibility to endometrial cancer(ENDMC) and ovarian cancer (OC).

Research Area

Epigenetics & Chromatin

Images & Validation

Tested ApplicationsWB
Dilution RangeWB:1:500-1:1000
ReactivityHuman

Key Properties

HostRabbit
ClonalityPolyclonal
ImmunogenC-terminal region of human CDH1
Molecular Weight97
PurityAffinity purification
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives0.01% NaN3
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anti-CDH1 antibody,anti-Cadherin1 antibody,anti-CAM 120 antibody,anti-80 antibody,anti-Epithelial cadherin antibody,anti-Ecadherin antibody,anti-Uvomorulin antibody,anti-CD324 antibody,anti-CDHE antibody,anti-UVO antibody
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UniProt Details

No UniProt data available

Protocol Information

WB
Western Blot (IB, immunoblot)
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100 μl
$ 440.00
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Free Secondary Antibody (20 ul)0/0

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