CDK2/FLT4/PDGFRA-IN-1

SKU: orb3028305

Description

CDK2/FLT4/PDGFRA-IN-1 (Compound 4a) is a potent inhibitor of CDK2/cyclin A, FLT4 (VEGFR3), and PDGFRA, with IC50 values of 1.672, 0.554, and 0.629 μM respectively. This compound demonstrates significant antiproliferative effects on cancer cells, including lung cancer EBC-1, pancreatic ductal adenocarcinoma AsPC-1, and colorectal cancer HT-29 cells. Additionally, CDK2/FLT4/PDGFRA-IN-1 can induce apoptosis in these cancer cells.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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Target	CDK,Apoptosis,PDGFR,VEGFR

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

CDK,Apoptosis,PDGFR,VEGFR

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