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CDKI-83

SKU: orb1738193

Description

CDKI-83 is a potent and selective CDK9 inhibitor with anti-proliferative activity (GI50 <1 μM) in tumor cell lines. It induces apoptosis in A2780 ovarian cancer cells, evidenced by caspase-3 activation and sub-G1 accumulation, suggesting potential as an anticancer agent through combined CDK9/CDK1 inhibition.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1189558-88-0
MW485.58
FormulaC21H23N7O3S2
SMILESC(#N)C=1C(=NC(NC2=CC(S(=O)(=O)N3CCOCC3)=C(C)C=C2)=NC1)C=4SC(NC)=NC4C
TargetCDK,Others,Bcl-2 Family,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

CDKI-83 (orb1738193)

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