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Cedirogant

SKU: orb1297964

Description

Cedirogant (ABBV-157) is an orally bioavailable, small molecule inverse agonist of the retinoid-related orphan receptor γt (RORγt). It is utilized in preclinical and clinical research for autoimmune conditions like psoriasis, investigating its mechanism and efficacy in modulating IL-17-driven inflammatory pathways.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2055496-11-0
MW547.78
Purity99.57%
FormulaC24H20Cl3F3N2O3
SMILESOC(=O)CC1CCN(CC1)C(=O)c1ccc(Cl)c(Cn2ccc3cc(cc(Cl)c23)C(F)(F)F)c1Cl
TargetROR
SolubilityDMSO:200 mg/mL (365.11 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.13 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, inverse, Cedirogant, agonist, ABBV157, ABBV-157, ABBV 157, RAR-related orphan receptor, RORγt, ROR, psoriasis
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Key Properties

No computed properties available.

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Protocol Information

Cedirogant (orb1297964)

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% DMSO +
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% Tween 80 +
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Available Sizes

Select a size below

1 mg
¥ 1,560.00
5 mg
¥ 2,860.00
1 ml x 10 mM (in DMSO)
¥ 3,380.00
10 mg
¥ 4,290.00
25 mg
¥ 7,410.00
50 mg
¥ 10,790.00
100 mg
¥ 15,600.00
200 mg
¥ 20,800.00
DispatchUsually dispatched within 3-5 working days
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