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CGP 55845

SKU: orb1738949

Description

CGP 55845 is a potent and selective GABAB receptor antagonist with a pKi of 8.35, effectively blocking agonist binding. It inhibits the release of GABA and glutamate, demonstrated by pEC50 values of 8.08 and 7.85, respectively. This compound is widely used in neuroscience research to study synaptic transmission and neurotransmitter release in both in vitro and in vivo models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number150175-54-5
MW402.25
FormulaC18H22Cl2NO3P
SMILES[C@H](NC[C@@H](CP(CC1=CC=CC=C1)(=O)O)O)(C)C2=CC(Cl)=C(Cl)C=C2
TargetGABA Receptor,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

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25 mg
$ 1,860.00
50 mg
$ 2,420.00
100 mg
$ 3,140.00
DispatchUsually dispatched within 8-10 weeks
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