CHEK1 (C) Antibody, Rabbit Polyclonal

SKU: orb67288

Description

Rabbit polyclonal to CHEK1.Serine/threonine-protein kinase Chk1 (CHEK1) belongs to the CAMK Ser/Thr protein kinase family.CHEK1 is required for checkpoint mediated cell cycle arrest in response to DNA damage or thepresence of unreplicated DNA. CHEK1 also acts to integrate signals from A and ATR, two cellcycle proteins involved in DNA damage responses, that also associate with chromatin in meioticprophase I. Phosphorylation of CDC25A protein phosphatase by CHEK1 is required for cells to delaycell cycle progression in response to double-strand DNA breaks.

Research Area

Epigenetics & Chromatin

Images & Validation

−

Item 1 of 1

Tested Applications	WB
Dilution Range	WB:1:500-1:1000
Reactivity	Human

Key Properties

−

Host	Rabbit
Clonality	Polyclonal
Immunogen	C-terminal region of human CHEK1
Molecular Weight	54
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

−

Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

−

anti-CHEK1 antibody,anti-Serine antibody,anti-threonineprotein kinase Chk1 antibody,anti-CHK1 antibody,anti-CHK1 checkpoint homolog antibody,anti-Cell cycle checkpoint kinase antibody,anti-Checkpoint kinase1 antibody

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Western blot analysis of total cell extracts from human Jurkat using CHEK1 antibody

Quick Database Links

UniProt

O14757

UniProt Details

−

No UniProt data available

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Western Blot (IB, immunoblot)

View Protocol

Find More Protocols