Chloroguanabenz acetate

SKU: orb3136435

Description

Chloroguanabenz (acetate) is an antiprion agent derived from guanabenz, an α2-adrenergic receptor agonist. It inhibits prion formation in vitro in both yeast and mammalian models. Additionally, Chloroguanabenz (acetate) reduces levels of the truncated huntingtin protein derivative Htt48 in HEK293T cells and is used for studying Huntington's disease.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	2242615-97-8
MW	325.58
Formula	C₁₀H₁₁Cl₃N₄O₂
SMILES	C(C)(O)=O.C(=N/NC(=N)N)\C1=C(Cl)C(Cl)=CC=C1Cl
Target	Adrenergic Receptor

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

Adrenergic Receptor

Protocol Information