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Cichoriin

SKU: orb1297115

Description

Cichoriin is a natural photosensitizing agent suitable for research in photodynamic therapy. It has been investigated in vivo for the treatment of benign mammary tumors in rodent models. This compound is also used in vitro to study its light-activated mechanisms and potential therapeutic applications.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number531-58-8
MW340.28
Purity>99.99% (May vary between batches)
FormulaC15H16O9
SMILESOC[C@H]1O[C@@H](Oc2cc3oc(=O)ccc3cc2O)[C@H](O)[C@@H](O)[C@@H]1O
TargetSARS-CoV,Others
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.88 mM);DMSO:60 mg/mL (176.33 mM)

Bioactivity

In Vitro
METHODS AND RESULTS:Four flavonoids including kaempferol (1), isoscutellarin (2), umbelliferone (3) and Cichoriin (4) have been isolated from Streptomyces sp. Tc052, an endophyte in the root tissue of Alpinia galanga Swartz. The evaluation for protective effect of compounds 1-4 against glutamate-induced cytotoxicity in hippocampal HT22 cell line was conducted, Compounds 1 and 2 showed significant effective protection ratios of 62.4+2.8 and 55.3+3.4%, respectively, at a concentration of 100 μM, whereas compounds 3-4 were inactive. Compounds 1 and 2 showed potent scavenging effects on DPPH radical exhibiting IC50 value of 60.74 and 75.65 μM, respectively. CONCLUSIONS: These results suggest that compounds 1 and 2 may possess the neuroprotective activity against oxdative cellular injuries.

Storage & Handling

Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, Cichoriin, SARS coronavirus, SARS-CoV
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Key Properties

No computed properties available.

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Cichoriin (orb1297115)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 1,300.00
5 mg
¥ 2,210.00
1 ml x 10 mM (in DMSO)
¥ 2,470.00
10 mg
¥ 3,120.00
25 mg
¥ 5,070.00
50 mg
¥ 7,280.00
100 mg
¥ 10,140.00
DispatchUsually dispatched within 3-5 working days
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