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Cintirorgon

SKU: orb1296278

Description

Cintirorgon

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2055536-64-4
MW603.53
Purity99.92% (May vary between batches)
FormulaC27H23F6NO6S
SMILESCC(C)(C[C@H]1CN(c2cc(ccc2O1)-c1cc(F)cc(OC(F)F)c1)S(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O
TargetROR
Solubility10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (5.47 mM);DMSO:110 mg/mL (182.26 mM)

Bioactivity

In Vitro
Upon oral administration of Cintirorgon, this agent selectively binds to the nuclear receptor transcription factor RORγ, forming a receptor complex that translocates to the nucleus, and binds to ROR response elements (ROREs), enhancing the function, proliferation and survival of type 17 T cells, including Th17 (helper T cells) and Tc17 (cytotoxic T cells). RORγ, the nuclear receptor transcription factor that is involved in Th17/Tc17 differentiation, plays a key role in immune activation.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

RORγ, ROR, RAR-related orphan receptor, Cintirorgon, LYC 55716, LYC55716, LYC-55716, inhibit, Inhibitor

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 180.00
1 ml x 10 mM (in DMSO)
$ 230.00
10 mg
$ 240.00
25 mg
$ 390.00
50 mg
$ 540.00
100 mg
$ 730.00
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