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Cletoquine hydrochloride

SKU: orb1710030

Description

Cletoquine hydrochloride, a primary active metabolite and chloroquine derivative of hydroxychloroquine, demonstrates antimalarial activity and has shown antiviral efficacy against chikungunya virus (CHIKV) in research settings, supporting its investigation in virology and parasitology.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number159358-29-9
MW344.28
Purity98.40% (May vary between batches)
FormulaC16H23Cl2N3O
SMILESClC1=CC2=NC=CC(NC(CCCNCCO)C)=C2C=C1.Cl
TargetParasite,Influenza Virus
SolubilityDMSO:4 mg/mL (11.62 mM)

Bioactivity

In Vivo
Hydroxychloroquine (5 mg/kg; intravenously) is administered to BALB/c mice for blood and tissue to determine the content of Cletoquine. The tissue to blood concentration ratio (Kp) is ≥1, indicating accumulation of Cletoquine in tissues. The Cletoquine Kp ratio for the various tissues are observed of liver (114.3)>kidney (24.4)>spleen (19.3)>lungs (16.5)>heart (5.5).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Influenza virus, Influenza Virus, InfluenzaVirus, Parasite, Cletoquine Hydrochloride, Cletoquine hydrochloride( 4298-15-1 Free base)
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 120.00
5 mg
$ 220.00
1 ml x 10 mM (in DMSO)
$ 240.00
10 mg
$ 280.00
25 mg
$ 400.00
50 mg
$ 520.00
100 mg
$ 670.00
DispatchUsually dispatched within 3-5 working days
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